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Abstract

The demand for recombinant therapeutic proteins has increased significantly, creating an ongoing need to enhance existing expression systems and develop new approaches to meet this growing demand. Initially, therapeutic proteins were extracted from human tissues or blood. However, this method presents several disadvantages, such as insufficient biological material for industrial-scale production and the risk of contamination by pathogens. As a result, the use of genetically engineered products has become a safer alternative. Since the advent of recombinant DNA technology, recombinant bacterial expression systems, particularly Escherichia coli (E. coli), have played a central role in the production of therapeutic proteins. This discussion focuses on recombinant therapeutic proteins, with a particular emphasis on those produced in E. coli, which have seen widespread use in the industry.

Keywords

Escherichia Coli Expression Systems Recombinant Insulin Recombinant Technology Therapeutic Proteins

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Lemar, G. S. (1403). Investigating the Production of Therapeutic Proteins Using Microbes. Journal of Natural Sciences – Kabul University, 7(4), 371–387. https://doi.org/10.62810/jns.v7i4.423
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