Main Article Content

Abstract

The liver is the largest gland in the body. Blood passes through the liver sinusoids and ultimately leaves the liver via the hepatic veins, which drain into the vena cava. The liver sinusoids remove bacteria and other particulate matter that may enter the blood from the gastrointestinal tract. The liver holds a unique position concerning the venous blood from the portal vein, which drains blood from the gastrointestinal tract through the liver before entering the general circulation. The portal vein is the primary afferent vessel and supplies most of the blood to the liver. The portal venous system is defined as one that begins and ends in capillaries. The name "portal vein" applies to the venous system that originates in the capillaries of the intestine and terminates in the hepatic sinusoids.

Keywords

Blood Circulation Caudal Mesenteric Vein Celiac Vein Cranial Mesenteric Vein Portal Vein

Article Details

How to Cite
Hamid, A. (2025). Anatomical Study of the Portal Venous System. Journal of Natural Sciences – Kabul University, 3(3), 159–166. https://doi.org/10.62810/jns.v3i3.176

References

  1. Carneiro C, Brito J, Bilreiro C, Barros M, Bahia C, Santiago I, Caseiro-Alves F. All about portal vein: a pictorial display to anatomy, variants and physiopathology. Insights Imaging. 2019:(1):38.
  2. Lautt WW. Hepatic Circulation: Physiology and Pathophysiology. Morgan & Claypool Life Sciences; San Rafael (CA): 2009.
  3. Covey AM, Brody LA, Getrajdman GI, Sofocleous CT, Brown KT. Incidence, patterns, and clinical relevance of variant portal vein anatomy. AJR Am J Roentgenol 2004;183(4):1055–1064.
  4. Gallego C, Velasco M, Marcuello P, Tejedor D, De Campo L, Friera A. Congenital and acquired anomalies of the portal venous system. Radiographics. 2002;22(1):141-59.
  5. Takayasu K, Moriyama N, Muramatsu Y, et al. Intrahepatic portal vein branches studied by percutaneous transhepatic portography. Radiology 1985;154(1):31–36.
  6. Ishiyama S, Yamada Y, Narishima Y, et al. Surgical anatomy of the hilar bile duct. Tan to Sui 1999;20:811–820.
  7. Douglas BE, Baggenstoss AH, Hollinshead WH. The anatomy of the portal vein and its tributaries. Surg Gynecol Obstet 1979;91:562–576.
  8. Vianna A, Hayes PC, Moscoso G, et al. Normal venous circulation of the gastresophageal junction. A route to understanding varices. Gastroenterology 1987;93:876–889.
  9. Thornburg B, Desai K, Hickey R, Kulik L, Ganger D, Baker T, Abecassis M, Lewandowski RJ, Salem R. Portal Vein Recanalization and Transjugular Intrahepatic Portosystemic Shunt Creation for Chronic Portal Vein Thrombosis: Technical Considerations. Tech Vasc Interv Radiol. 2016;19 (1):52-60.
  10. Simonetto DA, Liu M, Kamath PS. Portal Hypertension and Related Complications: Diagnosis and Management. Mayo Clin. Proc. 2019;94(4):714-726.
  11. Piron L, Deshayes E, Escal L, Souche R, Herrero A, Pierredon-Foulongne MA, Assenat E, le Lam N, Quenet F, Guiu B. [Portal vein embolization: Present and future]. Bull Cancer. 2017;104(5):407-416.
  12. Wisse E, De Zanger RB, Jacobs R, McCuskey RS. Scanning electron microscope observations on the structure of portal veins, sinusoids and central veins in rat liver. Scan Electron Microsc 1983;3: 1441–1452.
  13. Pillebout E. [Hepatorenal syndrome]. Nephrol. Ther. 2014;10(1):61-8.
  14. Thornburg B, Desai K, Hickey R, Hohlastos E, Kulik L, Ganger D, Baker T, Abecassis M, Caicedo JC, Ladner D, Fryer J, Riaz A, Lewandowski RJ, Salem R. Pretransplantation Portal Vein Recanalization and Transjugular Intrahepatic Portosystemic Shunt Creation for Chronic [7]. Portal Vein Thrombosis: Final Analysis of a 61-Patient Cohort. J Vasc Interv Radiol. 2017;28(12):1714-1721.
  15. Haris M, Thachil J. Portal vein thrombosis - a primer for the general physician. Clin Med (Lond). 2017;17(3):212-219.
  16. Basit SA, Stone CD, Gish R. Portal vein thrombosis. Clin Liver Dis. 2015;19(1):199-221.
  17. Nopanitayo W, Grisham JW, Aghajanian JG, Carso JL. Intrahepatic microcirculation: SEM study of the terminal distribution of the hepatic artery. Scan Electron Microsc 1978;11:837–842.
  18. Yamamoto K, Sherman I, Phillips MJ, Fisher MM. Three-dimensional observation of the hepatic arterial terminations in the rat, hamster and human liver by scanning electron microscopy of microvascular casts. Hepatology 1985;5:452–456.
  19. Ternberg JL, Butcher HR Jr. Blood-flow relation between hepatic artery and portal vein. Science 1965; 150:1030,1031.
  20. Kawasaki T, Carmichael FJ, Saldivia V, Roldan L, Orrego H. Relationship between portal venous and hepatic arterial blood flows. Spectrum of response. Am J Physiol 1990;259:1010–1018.
  21. Braet F, Wisse E. Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review. Comp Hepatol 2002;1:1–17.
  22. De Leeuw AM, Brouwer A, Knook DL. Sinusoidal endothelial cells of the liver: fine structure and function in relation to age. J Electron Microsc Tech 1990;14:218–236.
  23. Pinzani M, Gentilini P. Biology of hepatic stellate cells and their possible relevance in the pathogenesis of portal hypertension in cirrhosis. Semin Liver Dis 1999;397–410.
  24. Crissinger KD, Granger DN. Gastrointestinal blood flow. In: Yamada T, et al., eds. Textbook of Gastroenterology. Lippincott-Williams & Wilkins, Philadelphia, PA, 1999, p. 519.
  25. Granger DN, Kvietys PR, Korthuis R, Premen AJ. Microcirculation of the intestinal mucosa. In: Wood JD, ed. Handbook of Gastrointestinal Physiology. American Physiological Society, 1989, pp. 1405–1474.
  26. Granger DN, Holm L, Kvietys P. The Gastrointestinal Circulation: Physiology and Pathophysiology. Compr Physiol. 2015;5(3):1541-83.
  27. Kitami M, Takase K, Murakami G, et al. Types and frequencies of biliary tract variationsassociated with a major portal venous anomaly: analysis with multi-detector row CT cholangiography. Radiology 2006;238(1):156–166.
  28. Koc Z, Oguzkurt L, Ulusan S. Portal vein variations: clinical implications and frequencies in routine abdominal multidetector CT. Diagn Interv Radiol 2007;13(2):75–80.
  29. 29 Soyer P, Bluemke DA, Choti MA, Fishman EK. Variations in the intrahepatic portions of the hepatic and portal veins: findings on helical CT scans during arterial portography. AJR Am J Roentgenol 1995;164(1):103–108.
  30. Lucidarme O, Taboury J, Savier E, et al. Fusion of the midplane with the left intersectional plane: a liver anatomical variation revisited with multidetector-row CT. Eur Radiol 2006;16(8):1699–1708.